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Silodosin

Silodosin 8MG

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What is Silodosin?

Silodosin is a medication primarily used to treat the symptoms of benign prostatic hyperplasia (BPH), also known as enlarged prostate. As a selective alpha-1 adrenergic receptor antagonist, Silodosin works by relaxing the muscles in the bladder neck and prostate, improving urine flow and reducing BPH symptoms. This drug is typically administered orally and should be taken as prescribed by a healthcare provider.

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What is Silodosin ?

Silodosin is a medication primarily used to treat the symptoms of benign prostatic hyperplasia (BPH), also known as enlarged prostate. As a selective alpha-1 adrenergic receptor antagonist, Silodosin works by relaxing the muscles in the bladder neck and prostate, improving urine flow and reducing BPH symptoms. This drug is typically administered orally and should be taken as prescribed by a healthcare provider.
  • Lightheadedness, dizziness, fainting
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • This medicine is not for use in women.
  • Tell your doctor if you have kidney disease, liver disease, low blood pressure, or prostate cancer.
  • This medicine may make you dizzy or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel dizzy, so you do not faint.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your eye doctor (ophthalmologist) that you have used or are using this medicine before cataract surgery or any other eye procedure. This medicine may cause a serious eye problem called Intraoperative Floppy Iris Syndrome (IFIS).
What is silodosin used for?
Silodosin is FDA-approved to treat the signs and symptoms of benign prostatic hyperplasia (BPH), an enlarged prostate, in men. It relaxes muscle in the prostate and bladder neck to improve urine flow and ease symptoms such as weak, difficult, or frequent urination and urgency. It manages symptoms but does not cure BPH.
Is silodosin the same as Rapaflo?
Yes. Silodosin is the generic name and Rapaflo is the brand name for the same medicine. An FDA-approved generic silodosin is available and is typically less expensive than the brand. Both contain the same active ingredient and work the same way.
What are the most common side effects of silodosin?
The most common side effect is a change in ejaculation, often reduced or retrograde ejaculation. Other possible effects include dizziness, lightheadedness, a stuffy or runny nose, diarrhea, and a drop in blood pressure when standing. Contact your provider about side effects that bother you or do not go away.
Why does silodosin cause ejaculation problems?
Silodosin blocks alpha-1A receptors that are found in the prostate and bladder neck. Blocking these receptors relaxes muscle to improve urine flow, but it can also relax the muscle that normally closes off the bladder during ejaculation. As a result semen may flow backward into the bladder (retrograde ejaculation). This is not harmful and usually reverses if the medicine is stopped.
Can silodosin be used to help pass a kidney stone?
Silodosin is sometimes prescribed off-label as medical expulsive therapy to help pass a stone in the lower (distal) ureter, because it relaxes muscle in the urinary tract. This is not an FDA-approved use, so only take silodosin for this purpose if your own provider specifically recommends it.
How much does Silodosin cost without insurance?
The price of Silodosin without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 90% off retail prices with a free Rx.com coupon.
What are the common side effects of Silodosin?
Common side effects of Silodosin may include: Lightheadedness, dizziness, fainting, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Silodosin?
Generic versions may be available for Silodosin. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Silodosin on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Silodosin?
The cheapest pharmacy for Silodosin depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Silodosin near you.

Silodosin Coupons & Prices

Silodosin 8MG

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Silodosin Capsule — prescription drug image
Prescription
Silodosin 8mg (30)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a silodosin coupon? Silodosin (the generic form of Rapaflo) is a prescription alpha-blocker used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia, or BPH) in men. Because it is a generic, silodosin is already one of the lower-cost options in its class, but the cash price can still vary widely from one pharmacy to the next. Rx.com compares prices across more than 60,000 pharmacies so you can find the lowest one near you. Enter your ZIP above to see today's price and get a free discount coupon you can use at the counter.

What is silodosin and how does it work?

Silodosin is a uroselective alpha-1A adrenergic blocker. It is FDA-approved to treat the signs and symptoms of benign prostatic hyperplasia (BPH), an enlarged prostate that is common in older men. Silodosin works by relaxing the smooth muscle in the prostate and the neck of the bladder. This eases the pressure on the urethra and improves urine flow, helping with symptoms like difficult, weak, or frequent urination and a sudden urge to go.

Silodosin does not shrink the prostate, so it does not cure BPH. It manages the symptoms while you keep taking it. Your provider may sometimes prescribe silodosin off-label to help pass a kidney stone; only take it for a use your own provider has recommended.

Silodosin cost and savings without insurance

Silodosin is available as an FDA-approved generic of the brand Rapaflo, which usually makes it far more affordable than the brand. Even so, the cash price is not the same everywhere. The same prescription can cost noticeably more at one pharmacy than at another just a few blocks away, so comparing prices genuinely matters, especially if you are paying without insurance.

Rx.com checks prices across more than 60,000 U.S. pharmacies and gives you a free discount coupon to bring to the pharmacy counter. Enter your ZIP above to see today's price near you. If you prefer the brand, the maker of Rapaflo offers a manufacturer savings program on its official site, rapaflo.com; eligibility and terms vary, and such offers generally cannot be combined with a discount coupon.

Silodosin vs. other alpha-blockers

Silodosin is one of several alpha-blockers used for BPH. It is considered uroselective, meaning it targets the alpha-1A receptors concentrated in the prostate and bladder. Other alpha-blockers work in a similar way but differ in how they are dosed and in their side-effect profiles. Your provider chooses among them based on your other health conditions, blood pressure, and how you tolerate the medicine.

  • Tamsulosin (Flomax) - another uroselective alpha-blocker widely used for BPH.
  • Alfuzosin - a once-daily extended-release alpha-blocker.
  • Doxazosin - an older alpha-blocker that also lowers blood pressure.
  • Terazosin - another older alpha-blocker used for BPH and blood pressure.
  • Rapaflo - the brand-name version of silodosin.

Compare prices on any of these with your ZIP above. This is general information, not medical advice; talk with your provider about which option fits you.

Safety and side effects

Silodosin has no boxed warning. The most common side effect is a change in ejaculation, often reduced or absent (retrograde) ejaculation, which is not harmful and usually reverses if the drug is stopped. Silodosin can also lower blood pressure, causing dizziness, lightheadedness, or fainting, especially with the first dose or when standing up. Avoid driving or hazardous tasks until you know how it affects you.

Tell your eye surgeon that you take or have taken silodosin before any cataract or glaucoma surgery, because it is linked to a condition called Intraoperative Floppy Iris Syndrome. Seek emergency care for an erection lasting more than four hours (priapism). Silodosin should not be taken with strong CYP3A4 inhibitors (such as ketoconazole, clarithromycin, or ritonavir) or by people with severe kidney or liver problems, and it should be used with caution alongside ED drugs (PDE5 inhibitors) and other alpha-blockers, which can add to its blood-pressure-lowering effect. This is not a complete list; review your full medication list and history with your provider or pharmacist.

Sources & accuracy

This Silodosin information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Silodosin on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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