Xhance
Xhance 16ML of 93MCG/ACT
What is Xhance?
Xhance (fluticasone propionate) is a corticosteroid nasal spray designed specifically for the treatment of nasal polyps in adults. It utilizes an Exhalation Delivery System to help deliver the medication deep into the nasal passages, aiming to reduce swelling and inflammation. Xhance is prescribed for use twice daily, and its efficacy and safety have been established in clinical trials.Side Effects
- Bone pain
- Eye pain or vision changes
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, asthma, any infection (including tuberculosis, herpes infection of the eye), a recent exposure to measles or chickenpox, or a history of cataracts, glaucoma, or osteoporosis. Tell your doctor if you have had nose surgery, a nose injury, or a recent infection in your nose.
- This medicine may cause the following problems:Holes, ulcers, or bleeding inside the noseIncreased risk of infectionSlow wound healingCataracts or glaucomaProblems with the adrenal glandsLow bone mineral density, which may lead to osteoporosisSlow growth in children
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Call your doctor if your symptoms do not improve or if they get worse.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Prescription savings · · · ·
What is Xhance ?
Xhance (fluticasone propionate) is a corticosteroid nasal spray designed specifically for the treatment of nasal polyps in adults. It utilizes an Exhalation Delivery System to help deliver the medication deep into the nasal passages, aiming to reduce swelling and inflammation. Xhance is prescribed for use twice daily, and its efficacy and safety have been established in clinical trials.- Bone pain
- Eye pain or vision changes
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Sores or white patches inside the nose or mouth
- Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss
- Heavy or unexplained bleeding from your nose, bleeding that will not stop
- Burning, redness, swelling, or irritation around or inside your nose
- Fever, chills, cough, sore throat, body aches
- Tiredness, weakness, dizziness
- Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, asthma, any infection (including tuberculosis, herpes infection of the eye), a recent exposure to measles or chickenpox, or a history of cataracts, glaucoma, or osteoporosis. Tell your doctor if you have had nose surgery, a nose injury, or a recent infection in your nose.
- This medicine may cause the following problems:Holes, ulcers, or bleeding inside the noseIncreased risk of infectionSlow wound healingCataracts or glaucomaProblems with the adrenal glandsLow bone mineral density, which may lead to osteoporosisSlow growth in children
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Call your doctor if your symptoms do not improve or if they get worse.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Tiredness, weakness, dizziness
Xhance Coupons & Prices
Xhance 16ML of 93MCG/ACT
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Xhance prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 16ml of 93mcg/act · Box | 16 | $806.99 | $626.16 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Xhance (fluticasone propionate) is a prescription nasal spray for chronic rhinosinusitis, and if your doctor has prescribed it, an Xhance coupon from Rx.com can help you find the lowest price at a nearby pharmacy. Enter your ZIP above to see today's price.
What Is Xhance and How Does It Work?
Xhance is a brand-name corticosteroid nasal spray that uses a pressurized delivery device (the Exhalation Delivery System) to reach further into the nasal passages and sinuses than standard nasal sprays. It's FDA-approved for adults with chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic rhinosinusitis without nasal polyps (CRSsNP). The corticosteroid works by reducing inflammation and swelling in the nasal and sinus tissue.
Manufacturer Savings Card vs. an Rx.com Cash Coupon
Optinose, the maker of Xhance, offers an official patient savings program; terms, eligibility, and pharmacy participation vary, so check the current program directly through Optinose or your prescriber. Manufacturer copay cards like this one are generally limited to patients with commercial insurance and typically cannot be used with Medicare, Medicaid, or if you're uninsured. An Rx.com cash coupon works differently: it's not tied to insurance status, so it can be a useful backup if you're uninsured, on Medicare, or if the manufacturer card is declined at the counter.
There's no FDA-approved generic version of Xhance's exhalation-delivery formulation currently marketed in the US, so the cash coupon route (comparing pharmacy prices) is often the most direct way to manage cost for this specific product.
Alternatives and Related Treatments
- Standard fluticasone propionate nasal sprays (like generic Flonase) treat allergic rhinitis but are not FDA-approved for chronic rhinosinusitis with or without polyps the way Xhance is.
- Nasal saline rinses are commonly used alongside prescription nasal steroids for sinus symptom relief.
- Ask your doctor whether a standard nasal steroid or Xhance's exhalation-delivery system is the right fit for your specific diagnosis.
Safety Information
Common side effects of Xhance can include headache, nosebleed, and throat or sinus discomfort. As with other nasal corticosteroids, long-term use should be monitored by your provider, particularly for effects on nasal tissue. This is general information, not medical advice; talk with your doctor or pharmacist about whether Xhance is right for you.
This Xhance information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Xhance on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.
