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Miglitol Tablet — prescription drug image

Miglitol

Miglitol 25MG

What is Miglitol?

Miglitol is an oral antidiabetic medication that belongs to the class of drugs known as alpha-glucosidase inhibitors. It functions by slowing down the breakdown of complex carbohydrates into glucose, thereby reducing the rise in blood sugar levels after meals. Miglitol is primarily used in the management of type 2 diabetes, often in conjunction with diet and other medications.

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What is Miglitol ?

Miglitol is an oral antidiabetic medication that belongs to the class of drugs known as alpha-glucosidase inhibitors. It functions by slowing down the breakdown of complex carbohydrates into glucose, thereby reducing the rise in blood sugar levels after meals. Miglitol is primarily used in the management of type 2 diabetes, often in conjunction with diet and other medications.
  • Gas, diarrhea, or stomach discomfort
  • You may need to keep a supply of glucose tablets or gel with you to treat low blood sugar. Regular table sugar may not work as well for low blood sugar, because miglitol keeps your body from absorbing regular sugar quickly.
  • Make sure you know what to do if your blood sugar gets too low. Teach your friends, co-workers, or family members what they can do to help you if you have low blood sugar.
  • To keep your diabetes under control, follow the diet that your doctor ordered, exercise regularly, and test your urine or blood for sugar as your doctor ordered.
  • Talk to your doctor before using this medicine if you are pregnant or breastfeeding.
  • Because of the way miglitol works, it is likely to cause gas. This is normal and should get better over time.
  • Tell your doctor if you start to have more problems than usual with low blood sugar.
  • If your blood sugar gets too low, you may feel weak, drowsy, confused, or very hungry. You may also sweat, shake, or have blurred vision, a fast heartbeat, trouble concentrating, or a headache that won't go away.
  • Tell your doctor if you have kidney disease or any problems with digestion or your bowels.
  • Miglitol by itself does not cause low blood sugar the way some other medicines to treat diabetes can. But, if you also use other anti-diabetes medicine, miglitol can work with these other medicines to make your blood sugar even lower.
What is miglitol used for?
Miglitol is FDA-approved, along with diet and exercise, to help control blood sugar in adults with type 2 diabetes. It's taken with the first bite of each main meal and works by slowing carbohydrate absorption in the gut rather than by boosting insulin release. It isn't used for type 1 diabetes or diabetic ketoacidosis.
How does miglitol differ from metformin or acarbose?
Miglitol and acarbose are both alpha-glucosidase inhibitors that work the same way, by slowing carbohydrate breakdown in the intestine. Metformin works differently, mainly by reducing how much glucose the liver releases. Your provider can help decide which approach, or combination, fits your situation best.
What should I do if I have low blood sugar while taking miglitol?
Miglitol itself doesn't cause low blood sugar, but if you're also taking a sulfonylurea or insulin and low blood sugar occurs, treat it with glucose tablets or gel (dextrose), not table sugar. Miglitol blocks the breakdown of regular sugar, so sucrose won't raise your blood sugar quickly enough in that situation.
What are the side effects of miglitol (Glyset)?
The most common side effects are gastrointestinal: gas, diarrhea, and abdominal discomfort from carbohydrates fermenting in the gut. These often improve over time, and starting at a lower dose and increasing gradually can help reduce them. Talk with your provider if side effects are severe or don't improve.
Is Glyset still available, or only generic miglitol?
The Glyset brand has been discontinued in the US. Miglitol is now sold only as a generic medication.
How much does Miglitol cost without insurance?
The price of Miglitol without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Miglitol?
Common side effects of Miglitol may include: Gas, diarrhea, or stomach discomfort. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Miglitol?
Generic versions may be available for Miglitol. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Miglitol on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Miglitol?
The cheapest pharmacy for Miglitol depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Miglitol near you.

Miglitol Coupons & Prices

Miglitol 25MG

Miglitol Tablet — prescription drug image
Prescription
Miglitol 25mg (12)
your area ·

Looking for a miglitol coupon? Miglitol is the generic name for the oral diabetes medicine formerly sold under the brand Glyset, which has been discontinued in the US, so miglitol is now only available as a generic. Generic pricing can still vary a surprising amount from one pharmacy to the next, which is exactly why it pays to compare before you fill: Rx.com checks prices across 60,000+ pharmacies so you can enter your ZIP above and see today's price near you.

What Is Miglitol and How Does It Work?

Miglitol is an alpha-glucosidase inhibitor approved by the FDA as an add-on to diet and exercise to improve blood sugar control in adults with type 2 diabetes. It's typically taken three times a day, with the first bite of each main meal. Rather than increasing the amount of insulin your body makes, miglitol works in the gut, slowing how quickly complex carbohydrates from food are broken down and absorbed, which blunts the rise in blood sugar after eating.

Miglitol is not approved for type 1 diabetes and should not be used to treat diabetic ketoacidosis. It's generally considered a second- or third-line option today, used less often than some newer diabetes medicines.

Miglitol Cost Without Insurance

Because miglitol is only available generically now that Glyset has been discontinued, you're comparing generic-to-generic prices across pharmacies rather than choosing between a brand and a generic. Cash prices for generic drugs can still differ meaningfully by pharmacy and by location, so it's worth checking before you fill. Enter your ZIP code above to compare miglitol prices at pharmacies near you and find a price that works for your budget.

Miglitol vs. Other Diabetes Medicines

Miglitol belongs to a small class of drugs called alpha-glucosidase inhibitors, alongside acarbose, which works the same way in the gut. It's a different approach than metformin, which reduces the liver's glucose output, or sulfonylureas like glipizide and glyburide, which stimulate the pancreas to release more insulin. Other options your provider may consider include pioglitazone, which improves insulin sensitivity, and sitagliptin, a DPP-4 inhibitor. Which medicine (or combination) is right for you depends on your health history, other medications, and how your body responds, so talk with your provider about the best fit.

Miglitol Safety Information

Miglitol doesn't carry a boxed warning. The most common issues are digestive: gas, diarrhea, and stomach discomfort caused by undigested carbohydrate fermenting in the gut. These often ease over time, and starting at a low dose and increasing slowly can help. Miglitol itself doesn't cause low blood sugar, but if you're also taking a sulfonylurea or insulin and you do experience low blood sugar, it's important to treat it with glucose tablets or gel rather than table sugar, since miglitol blocks the body's ability to break down regular sugar (sucrose).

Miglitol shouldn't be used by people with inflammatory bowel disease, colon ulcers, partial bowel blockage, chronic digestive conditions that cause malabsorption, or a known allergy to the drug, and it requires caution in significant kidney impairment. This is general information, not medical advice — talk with your provider about whether miglitol is appropriate for you.

Sources & accuracy

This Miglitol information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Miglitol on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.