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Vemlidy

Vemlidy 30 Tablets

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What is Vemlidy?

Vemlidy is used in the treatment of chronic hepatitis B. There is not a generic version currently available for Vemlidy. The average price of Vemlidy is approximately $1,122 for a supply of 30, 25 mg tablets. You can use our free Singlecare savings card to receive a Vemlidy discount of up to 80% at a local pharmacy that participates with Singlecare.

Prescription savings · · · ·

What is Vemlidy ?

Vemlidy is used in the treatment of chronic hepatitis B. There is not a generic version currently available for Vemlidy. The average price of Vemlidy is approximately $1,122 for a supply of 30, 25 mg tablets. You can use our free Singlecare savings card to receive a Vemlidy discount of up to 80% at a local pharmacy that participates with Singlecare.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast breathing, trouble breathing, lightheadedness, severe weakness, tiredness, confusion
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Change in how much or how often you urinate, cloudy urine
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • This medicine may cause the following problems:Lactic acidosis (too much acid in the blood)Severe liver problemsWorsening of hepatitis B infection (if the medicine is stopped)Kidney problems
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney problems or liver disease.
What is Vemlidy used for?
Vemlidy is FDA-approved to treat chronic hepatitis B virus (HBV) infection in adults and children 6 years and older who weigh at least 25 kg and have compensated liver disease. It is not approved to treat HIV.
Is Vemlidy the same as Viread or Descovy?
No. Viread (tenofovir disoproxil fumarate) is also FDA-approved for chronic hepatitis B and belongs to the same tenofovir family, but it's an older prodrug formulation dosed differently than Vemlidy. Descovy contains tenofovir alafenamide, the same active ingredient as Vemlidy, combined with emtricitabine, but Descovy is approved for HIV-1 treatment and prevention, not hepatitis B, so it isn't a substitute for Vemlidy.
How much does Vemlidy cost without insurance?
Vemlidy pricing varies by pharmacy and location, and there is currently no generic version. Enter your ZIP code above to see today's price near you. The manufacturer's savings card is generally limited to patients with commercial insurance, so if you're uninsured or on Medicare, the Rx.com cash coupon is worth comparing.
What are the side effects of Vemlidy?
The most commonly reported side effects include headache, upper respiratory infection, abdominal pain, cough, back pain, joint pain, fatigue, nausea, diarrhea, indigestion, and fever. Vemlidy also carries boxed warnings for lactic acidosis and severe liver problems, and for hepatitis B flare-ups after stopping the drug. Talk to your doctor about your full side-effect risk.
Can you stop taking Vemlidy once hepatitis B is under control?
Don't stop taking Vemlidy without talking to your doctor first. Vemlidy's FDA label carries a boxed warning that stopping the drug can trigger a severe flare-up of hepatitis B, so patients need close medical monitoring for at least several months after discontinuing it.
How much does Vemlidy cost without insurance?
The price of Vemlidy without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Vemlidy?
Common side effects of Vemlidy may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Fast breathing, trouble breathing, lightheadedness, severe weakness, tiredness, confusion, Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes, Change in how much or how often you urinate, cloudy urine. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Vemlidy?
Generic versions may be available for Vemlidy. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Vemlidy on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Vemlidy?
The cheapest pharmacy for Vemlidy depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Vemlidy near you.

Vemlidy Coupons & Prices

Vemlidy 30 Tablets

Prescriptions & Refills
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Vemlidy Bottle — prescription drug image
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Vemlidy (tenofovir alafenamide) is a brand-name antiviral FDA-approved to treat chronic hepatitis B virus (HBV) infection in adults and children 6 and older who weigh at least 25 kg and have compensated liver disease. There is currently no generic version, so shoppers searching for a Vemlidy coupon are really comparing the manufacturer's savings card against pharmacy discount programs. Enter your ZIP code above to see today's Vemlidy price at pharmacies near you — the Rx.com cash coupon can help whether or not you have insurance.

What Is Vemlidy and How Does It Work?

Vemlidy's active ingredient, tenofovir alafenamide, belongs to the nucleotide analog reverse transcriptase inhibitor class of antivirals — it's a prodrug form of tenofovir that concentrates in liver cells, where it works to suppress hepatitis B virus replication. Vemlidy is approved specifically for chronic HBV infection in adults and pediatric patients 6 years and older weighing at least 25 kg who have compensated liver disease.

Vemlidy is not approved to treat HIV, and it is not recommended for patients with decompensated (Child-Pugh B or C) liver disease. Only your doctor can confirm whether Vemlidy is appropriate for your situation.

Vemlidy Savings Card vs. the Rx.com Coupon

Gilead, the manufacturer, offers an official Vemlidy Savings Card program through its own website. Like most manufacturer copay cards, it's generally limited to patients with commercial (private) insurance, and eligibility rules and terms can change, so check the current details directly on Gilead's site before assuming you qualify.

If you're uninsured, on Medicare, or your manufacturer card is declined at the pharmacy counter, the Rx.com cash coupon is a separate option that works regardless of insurance status. Because Vemlidy has no generic equivalent yet, pricing can vary by pharmacy — enter your ZIP code above to compare and find a price near you.

Vemlidy vs. Viread, Descovy, and Other HBV Options

Vemlidy isn't the only tenofovir-based option for chronic hepatitis B. Viread (tenofovir disoproxil fumarate) is an older tenofovir prodrug also FDA-approved for chronic HBV; it's dosed differently and has a different kidney/bone safety profile than Vemlidy's tenofovir alafenamide, and a generic version of tenofovir disoproxil fumarate is also available. Entecavir (sold under the brand Baraclude) is a different class of oral antiviral — a nucleoside analog — and is another FDA-approved option for chronic hepatitis B your doctor may discuss with you.

Descovy shares one ingredient (tenofovir alafenamide) with Vemlidy, but it's combined with emtricitabine and is approved for HIV-1 treatment and prevention, not hepatitis B — it is not an interchangeable alternative to Vemlidy. Only your doctor can determine which HBV antiviral is right for you.

Safety Information and Side Effects

Vemlidy carries boxed warnings for lactic acidosis and severe hepatomegaly with steatosis, which have been fatal in some cases, and for severe acute exacerbation of hepatitis B after stopping the drug — your doctor will need to monitor your liver function closely for at least several months after you stop taking Vemlidy. Vemlidy should not be used in patients who also have HIV-1 unless it's part of a complete HIV treatment regimen, since using it alone in that setting can lead to HIV drug resistance.

The most common side effects (reported in 5% or more of patients) include headache, upper respiratory infection, abdominal pain, cough, back pain, joint pain, fatigue, nausea, diarrhea, indigestion, and fever. This isn't a complete list — talk with your doctor or pharmacist about your full medical history before starting Vemlidy, and don't stop taking it without medical guidance.

Sources & accuracy

This Vemlidy information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Vemlidy on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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