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Ztlido

ZTlido 30 Patch

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What is Ztlido?

ZTlido 30 Patch is a prescription medication used to relieve pain from post-herpetic neuralgia, which can occur after a shingles infection. It works by blocking pain signals from nerves.

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What is Ztlido ?

ZTlido 30 Patch is a prescription medication used to relieve pain from post-herpetic neuralgia, which can occur after a shingles infection. It works by blocking pain signals from nerves.

Source: MedlinePlus, U.S. National Library of Medicine

  • Redness, itching, burning, swelling, or blisters where the patch is applied
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease. Tell your doctor if you are allergic to any other medicine.
  • Do not use a heating pad, electric blanket, or other heat source over the patch. .
What is Ztlido used for?
Ztlido is a lidocaine topical system 1.8% that is FDA-approved in adults to relieve the nerve pain that can follow shingles, called post-herpetic neuralgia (PHN). It is applied to intact skin over the most painful area.
Is Ztlido the same as a lidocaine patch (Lidoderm)?
Both contain lidocaine, but they are not identical. Ztlido is a 1.8% topical system, while Lidoderm and generic lidocaine patches are 5%. Ztlido is designed to adhere well and deliver lidocaine using less drug. They have different instructions, so do not switch between them without your provider's guidance.
How long do you leave a Ztlido patch on?
Follow your provider's directions and the label. The label allows a maximum of 3 systems applied at once for up to 12 hours within any 24-hour period. Do not wear it longer than directed, as excess exposure can raise lidocaine levels in the blood.
Is there a generic version of Ztlido?
The FDA approved the first generic lidocaine topical system 1.8% in 2025, but it has not yet launched, so a substitutable generic is not available at pharmacies yet. Generic lidocaine patches do exist, but they are a different strength and product. Until the generic reaches shelves, a cash coupon or the manufacturer's savings program is usually how people lower the cost.
How much does Ztlido cost without insurance?
The cash price varies by pharmacy and location. Enter your ZIP above to see today's price near you with the free Rx.com coupon, which can help whether you are uninsured, have Medicare, or were declined a manufacturer card.
How much does Ztlido cost without insurance?
The price of Ztlido without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Ztlido?
Common side effects of Ztlido may include: Redness, itching, burning, swelling, or blisters where the patch is applied, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Ztlido?
Generic versions may be available for Ztlido. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Ztlido on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Ztlido?
The cheapest pharmacy for Ztlido depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Ztlido near you.

Ztlido Coupons & Prices

ZTlido 30 Patch

Prescriptions & Refills
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Ztlido Box — prescription drug image
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Ztlido prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
30 patch · Box 30 $457.99 $333.49

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a Ztlido coupon? Ztlido is a brand-name prescription topical anesthetic (lidocaine topical system 1.8%) FDA-approved to relieve the nerve pain that can follow shingles, known as post-herpetic neuralgia (PHN). An FDA-approved generic was cleared in 2025 but has not yet launched at pharmacies, so the brand can still be costly at the counter. The free Rx.com cash coupon on this page can lower what you pay whether or not you have insurance. Enter your ZIP above to see today's price at pharmacies near you.

What is Ztlido and how does it work?

Ztlido is a proprietary lidocaine topical system 1.8% applied to intact skin over the most painful area. Lidocaine is an amide-type local anesthetic that works right at the surface, calming the overactive nerve signals in the treated area rather than acting through the whole body. It is FDA-approved in adults for the relief of pain associated with post-herpetic neuralgia (PHN), the lingering nerve pain that can follow a shingles (herpes zoster) infection.

Ztlido is designed to stick well and deliver lidocaine using less drug than older 5% lidocaine patches, though it is meant for the same kind of localized nerve pain. Some clinicians use topical lidocaine systems for other localized pain conditions, but PHN is the only use Ztlido is FDA-approved for. Always follow your provider's directions for where and how long to wear it.

Ztlido cost: manufacturer savings card vs. Rx.com cash coupon

Ztlido is currently brand-only at the pharmacy, so there are two main ways people lower the cost. The maker of Ztlido runs an official manufacturer savings program (described on the Ztlido brand website) that can reduce the copay for some patients. Like most drug-company copay cards, it is generally limited to people with commercial (private) insurance and typically excludes those with Medicare, Medicaid, or other government coverage, and its terms and eligibility can change, so read the current rules carefully.

The Rx.com cash coupon on this page works differently. It is a cash-discount coupon, not insurance, so it can help if you are uninsured, if you have Medicare, or if a manufacturer card is declined or you do not qualify for it. You simply show the coupon at the pharmacy. Enter your ZIP above to see today's price near you, and compare that against your insurance copay or the manufacturer program to see which is lower for you.

Is there a generic? Ztlido vs. other lidocaine options

The FDA approved the first generic lidocaine topical system 1.8% in 2025, but it has not yet launched, so a substitutable generic is not available at pharmacies right now. Until it reaches shelves, you cannot swap Ztlido for a cheaper A-rated generic the way you can with many brand drugs. Ztlido is not the only topical lidocaine choice, though. Generic lidocaine patches are widely available, and the older 5% patch is sold as brand Lidoderm and as a generic lidocaine patch. These are different products with different strengths and instructions, so only switch with your provider's guidance.

For nerve pain like PHN, doctors also commonly prescribe oral medicines such as gabapentin or pregabalin, and some people use topical capsaicin. Each works differently and has its own trade-offs, so talk with your provider about which fits your situation. This is general information, not medical advice.

Ztlido safety and side effects

Ztlido has no boxed warning, but it must be used exactly as directed. Applying more systems than prescribed, wearing them longer than instructed, or placing them on broken or inflamed skin can raise blood lidocaine levels and, in rare cases, cause serious heart or nervous-system effects such as seizures or irregular heartbeat. The label limits use to a maximum of 3 systems at once for up to 12 hours in any 24-hour period. There is also a small risk of methemoglobinemia, a blood-oxygen problem; get medical care for pale, gray, or blue-tinged skin, headache, unusual tiredness, or shortness of breath, especially if you take other medicines that can cause it.

The most common side effects are application-site reactions such as redness or irritation. Avoid contact with the eyes, and use caution if you have liver problems or take certain heart-rhythm (Class I antiarrhythmic) medicines. Keep new and used systems away from children and pets, since used patches still contain lidocaine and must be thrown away safely. This is not a complete list of warnings, so read the label and ask your provider or pharmacist with any questions.

Sources & accuracy

This Ztlido information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Ztlido on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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