Enalapril-Hydrochlorothiazide Coupons & Prices

Looking for an enalapril-hydrochlorothiazide coupon? Enalapril maleate and hydrochlorothiazide is the generic form of Vaseretic, a fixed-dose combination tablet used to treat high blood pressure (hypertension). The generic is widely available and already inexpensive at many pharmacies, but the cash price still swings a great deal from one counter to the next, even within the same town. Rx.com compares cash prices at more than 60,000 pharmacies so you can see where your prescription costs the least. Enter your ZIP code above to see today's price near you and print, text, or email a free discount coupon. No insurance is required, and no membership is needed to use it.

What is enalapril-hydrochlorothiazide and how does it work?

Enalapril-hydrochlorothiazide is a single tablet that combines two blood pressure medicines that work in different ways. Enalapril is an ACE inhibitor. It is a prodrug, meaning the body converts it into its active form (enalaprilat), which then relaxes and widens blood vessels. Hydrochlorothiazide is a thiazide diuretic, or "water pill," which helps your kidneys remove extra salt and fluid. Together they lower blood pressure more than either drug does alone. It comes as 5 mg/12.5 mg and 10 mg/25 mg tablets.

One important point about how this product is meant to be used: the FDA label says the combination is not indicated for initial therapy. Doctors are supposed to first find the right dose of each ingredient separately, then switch you to the combination tablet for convenience once your blood pressure is well controlled on those matching doses. The enalapril ingredient belongs to a drug class studied in other conditions, but this combination product is approved only for high blood pressure. Follow your prescriber's directions and do not change doses on your own.

What enalapril-hydrochlorothiazide costs without insurance

Here is the honest picture. Because an FDA-approved generic of this exact combination is available, enalapril-hydrochlorothiazide is already one of the lower-cost blood pressure options at the pharmacy counter. That does not mean every pharmacy charges the same thing. Cash prices for the identical tablet, strength, and quantity can differ by a large margin between a big chain, a grocery store pharmacy, and an independent down the street, because each sets its own cash price. That is exactly why comparing is worth the two minutes it takes.

If you are paying cash, or if your plan's deductible or copay is higher than the discounted cash price, an Rx.com coupon can help. Enter your ZIP code above to see today's price at pharmacies near you, then bring the coupon to the counter and ask the pharmacist to run it. There is no manufacturer savings card for this medication, which is typical for an older generic. You cannot combine a discount coupon with insurance on the same fill, so it is worth checking both and using whichever is lower.

Alternatives and related medications

If enalapril-hydrochlorothiazide is not the right fit, or you simply want to compare prices, several closely related options exist. Only your prescriber can decide which is appropriate for you.

• Enalapril alone, or hydrochlorothiazide alone, if you do not need both ingredients or are still being titrated.
• Lisinopril-hydrochlorothiazide and benazepril-hydrochlorothiazide, other ACE inhibitor plus thiazide combinations. Lisinopril on its own is one of the most commonly prescribed ACE inhibitors.
• Losartan-hydrochlorothiazide, which pairs a thiazide with an ARB instead of an ACE inhibitor. ARBs are often used for people who cannot tolerate the dry cough that ACE inhibitors can cause.

Vaseretic is the brand name for this same enalapril and hydrochlorothiazide combination. Because a substitutable generic exists, most pharmacies will fill the generic, and it will almost always be the cheaper choice. Prices for every drug listed above vary by pharmacy too, so it is worth running each one through the price tool before you decide with your doctor.

Safety information you should know

Boxed warning, fetal toxicity: medicines that act on the renin-angiotensin system, including the enalapril in this tablet, can injure or kill a developing baby. Stop the medication and tell your doctor as soon as you know you are pregnant. Other important points from the label: it can cause angioedema, a swelling of the face, lips, tongue, throat, or limbs that can be life-threatening if the airway is involved, and which occurs more often in Black patients. It should not be used by anyone with a history of angioedema related to an ACE inhibitor, or hereditary or idiopathic angioedema. It can also cause low blood pressure and fainting (syncope was reported in about 1.3% of patients in trials), especially if you are dehydrated or low on salt.

Also worth knowing: this combination can raise potassium, so avoid potassium supplements and potassium-containing salt substitutes unless your doctor approves. It can affect kidney function, so your doctor will monitor your kidneys and electrolytes with blood tests. The hydrochlorothiazide ingredient can lower potassium, sodium, or magnesium, raise uric acid (gout), blood sugar, and cholesterol, make your skin more sensitive to sunlight, and rarely cause sudden nearsightedness or acute angle-closure glaucoma. A persistent dry cough is a common ACE inhibitor effect. Do not take it with aliskiren if you have diabetes, and never take it within 36 hours of a neprilysin inhibitor such as sacubitril/valsartan (Entresto). It is also not for people who produce no urine (anuria) or who are allergic to sulfonamides. Use caution with NSAIDs and lithium. This is a summary, not medical advice. Talk with your doctor or pharmacist about your full medication list and health history.