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Indomethacin Er Capsule — prescription drug image

Indomethacin Er

Indomethacin ER 75MG

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What is Indomethacin Er?

Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis. Indomethacin is a generic drug. On average, a supply of 120, 75 mg Indomethacin extended release capsules cost about $510. Get savings of up to 80% when you use our free prescription coupon card at any participating pharmacy near you.

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What is Indomethacin Er ?

Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis. Indomethacin is a generic drug. On average, a supply of 120, 75 mg Indomethacin extended release capsules cost about $510. Get savings of up to 80% when you use our free prescription coupon card at any participating pharmacy near you.
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Change in how much or how often you urinate
  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
  • Unusual bleeding, bruising, or weakness
  • Chest pain that may spread, trouble breathing, unusual sweating, fainting
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • Bloody or black, tarry stools, severe stomach pain, vomiting blood or something that looks like coffee grounds
  • Tell your doctor if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
  • Tell your doctor if you have kidney disease, liver disease, asthma, bleeding problems, heart disease, high blood pressure, heart failure, or a history of stomach or bowel problems (including bleeding or ulcers), depression, mental illness, epilepsy, or Parkinson disease. Tell your doctor if you smoke or drink alcohol.
  • This medicine may cause the following problems:Higher risk of blood clots, heart attack, stroke, or heart failureBleeding and ulcers in your stomach or intestinesLiver damageKidney damageSerious skin reactionsChanges in vision
  • Ovulation may be delayed in some women while this medicine is being used. Talk to your doctor if you have concerns about this.
  • This medicine may make you drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Unusual bleeding, bruising, or weakness
What is indomethacin ER used for?
Indomethacin extended-release is FDA-approved to relieve the signs and symptoms of moderate to severe rheumatoid arthritis (including acute flares), moderate to severe ankylosing spondylitis, and moderate to severe osteoarthritis, as well as acute painful shoulder caused by bursitis or tendinitis. It reduces inflammation, pain, swelling, and stiffness.
How is indomethacin extended-release different from regular indomethacin?
Both contain the same active NSAID medicine. The extended-release capsule releases the drug slowly over time, so it is usually taken fewer times per day than immediate-release indomethacin. Regular (immediate-release) indomethacin acts faster and is used for some conditions, such as gout, where the ER form is not recommended.
Can you take indomethacin ER for gout?
No. The extended-release form is not recommended for acute gouty arthritis. Immediate-release indomethacin is the form used for gout. Always follow your prescriber's instructions about which formulation to take.
What are the most common side effects of indomethacin ER?
Common side effects can include headache, dizziness, and stomach upset. More serious risks include gastrointestinal bleeding or ulcers, cardiovascular events such as heart attack or stroke, high blood pressure, fluid retention and swelling, and effects on the kidneys or liver. Contact your provider right away if you notice black or bloody stools, chest pain, shortness of breath, or unusual swelling.
How often do you take indomethacin extended-release capsules?
Because the extended-release capsule releases medicine slowly, it is taken less often than regular indomethacin. The exact schedule depends on your prescription, so follow the directions on your label and your provider's guidance, and use the lowest effective dose for the shortest time needed.
How much does Indomethacin Er cost without insurance?
The price of Indomethacin Er without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Indomethacin Er?
Common side effects of Indomethacin Er may include: Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes, Change in how much or how often you urinate, Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking, Unusual bleeding, bruising, or weakness, Chest pain that may spread, trouble breathing, unusual sweating, fainting. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Indomethacin Er?
Generic versions may be available for Indomethacin Er. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Indomethacin Er on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Indomethacin Er?
The cheapest pharmacy for Indomethacin Er depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Indomethacin Er near you.

Indomethacin Er Coupons & Prices

Indomethacin ER 75MG

Prescriptions & Refills
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Indomethacin Er Capsule — prescription drug image
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Indomethacin Er prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
75mg · Capsule 30 $91.99 $16.67

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for an indomethacin ER coupon? Indomethacin extended-release is a generic prescription NSAID, and because it is already available as a low-cost generic, your cash price can vary widely from one pharmacy to the next. Rx.com compares free discount prices across more than 60,000 U.S. pharmacies, so you can find today's best price on indomethacin ER capsules near you. Enter your ZIP above to see today's price.

What is indomethacin ER and how does it work?

Indomethacin extended-release (brand name Indocin SR) is a nonsteroidal anti-inflammatory drug, or NSAID. It works by lowering the substances in the body that cause inflammation, pain, swelling, and stiffness. The extended-release capsule releases the medicine slowly over time, so it can be taken fewer times per day than regular indomethacin.

It is FDA-approved to relieve the signs and symptoms of moderate to severe rheumatoid arthritis (including acute flares of long-standing disease), moderate to severe ankylosing spondylitis, and moderate to severe osteoarthritis. It is also approved for the relief of acute painful shoulder from bursitis or tendinitis. Indomethacin is a well-established generic, so no brand-name product is required to get treatment.

Indomethacin ER cost and coupons without insurance

Indomethacin ER is a generic, which usually keeps its cash price lower than a brand-name drug. Even so, what you actually pay without insurance can differ a lot depending on which pharmacy you use, so it pays to compare. There is no manufacturer savings card for this generic; instead, a free Rx.com discount coupon can be used at the pharmacy counter whether or not you have insurance.

To see real, up-to-date pricing, enter your ZIP above to see today's price. Rx.com checks prices across more than 60,000 pharmacies and shows you the lowest available discount price near you, along with the free coupon to bring to the pharmacy.

Alternatives and related NSAIDs

Indomethacin ER is one of several NSAIDs used for arthritis and inflammatory pain. If you and your provider are weighing options, other commonly prescribed NSAIDs include the immediate-release form, indomethacin, along with naproxen, meloxicam, celecoxib, and diclofenac. Each has its own dosing schedule and side-effect profile.

Only your provider can decide which NSAID is right for you, but you can compare the cash price of each on Rx.com. Because all of these are available as generics, comparing pharmacies is often the biggest driver of what you pay.

Important safety information

This is general information, not medical advice; always follow your provider's directions. Like all NSAIDs, indomethacin carries a boxed warning. It may increase the risk of serious cardiovascular events such as heart attack and stroke, which can be fatal, and this risk may rise the longer it is used; it should not be used for pain right before or after heart bypass (CABG) surgery. It can also cause serious gastrointestinal bleeding, ulcers, and tears in the stomach or intestines, which can happen without warning and are more likely in older adults.

Use the lowest effective dose for the shortest time needed. Indomethacin can raise blood pressure, cause fluid retention and swelling, and affect the heart, kidneys, and liver. It should be avoided after 20 weeks of pregnancy, and especially in the third trimester. Avoid combining it with other NSAIDs, and use caution if you take blood thinners. Talk with your doctor or pharmacist about your full medical history before starting.

Sources & accuracy

This Indomethacin Er information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Indomethacin Er on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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