Morphine Sulfate Coupons & Prices

A morphine sulfate coupon from Rx.com can lower what you pay at the pharmacy counter when you are paying cash or your insurance does not cover your prescription. Morphine sulfate is a generic opioid pain medicine. Cash prices for the same tablets, capsules or oral solution can differ a lot from one pharmacy to the next, so it pays to compare before you fill rather than assume any one pharmacy is cheapest. Rx.com compares cash prices at pharmacies near you, including the big chains and neighborhood independents. Enter your ZIP code above to see today's price near you and print, text or email your free coupon. Morphine sulfate is a Schedule II controlled substance and requires a prescription from your doctor.

What is morphine sulfate and how does it work?

Morphine sulfate is an opioid agonist analgesic. It is a natural opioid (a phenanthrene derivative) that works by attaching to mu-opioid receptors in the brain and spinal cord, which changes the way your nervous system senses and responds to pain. It is FDA-approved for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

Morphine sulfate comes in several forms, and they are not interchangeable:

• Immediate-release tablets and oral solution - used for acute or around-the-clock pain, generally taken about every 4 hours.
• Extended-release tablets (MS Contin and generic morphine sulfate ER tablets) and extended-release capsules (generic morphine sulfate ER capsules) - used for around-the-clock, long-term treatment of severe pain, such as cancer pain or hospice and palliative care. The label states these products are not for as-needed (PRN) pain. Most strengths can be started in patients who are not opioid-tolerant with careful titration, but the higher doses are restricted: for MS Contin, a single dose greater than 60 mg, or a total daily dose greater than 120 mg, is only for patients already tolerant to an opioid of comparable potency.
• Injectable forms - used in medical settings for severe acute pain, including epidural and intrathecal use for surgical and intractable chronic pain.

Brand availability has changed over time. MS Contin is still marketed as an extended-release tablet, but several other morphine brands - including MorphaBond ER, Kadian, Arymo ER and the Roxanol oral solution brand - are no longer marketed in the U.S. Generic morphine sulfate extended-release tablets and capsules, immediate-release tablets and oral solution remain available. This information is educational and is not medical advice - your prescriber decides which form and strength is right for you.

Morphine sulfate cost without insurance, and how to save

There is no one price for morphine sulfate. Cash prices for the identical prescription can vary widely between pharmacies in the same town, and immediate-release tablets, extended-release tablets and capsules, and oral solution are all priced differently. Your final price also depends on the strength, the quantity your doctor writes for, and where you fill. That is exactly why comparing matters. Enter your ZIP code above to see today's price at pharmacies near you.

There is no manufacturer savings card for generic morphine sulfate. A free Rx.com coupon is a cash-discount card you show at the pharmacy instead of using insurance, and you can use it even if you are uninsured, have a high deductible, or your plan does not cover this medicine. You cannot combine a coupon with insurance on the same fill, so ask the pharmacist which price is lower. Because morphine sulfate is a Schedule II controlled substance, refills are not allowed on the same prescription and pharmacies have extra dispensing rules - your coupon lowers the cash price, but it does not change those rules. If you take morphine long term, ask your prescriber and pharmacist whether a 30-day supply of a common strength is a more affordable way to fill.

Morphine sulfate vs. other opioid pain medicines

Morphine is one of several opioid analgesics your doctor may consider. Others include oxycodone (also sold as extended-release OxyContin), hydrocodone-acetaminophen, hydromorphone, tramadol, and methadone. They differ in strength per milligram, how long they last, how they are broken down by the body, and how they are dosed, so switching between them is never a simple milligram-for-milligram swap. The metabolism differences matter for interactions, too: morphine is cleared mainly by glucuronidation rather than by the CYP3A4 enzyme system, so the CYP3A4 drug-interaction warnings that appear on oxycodone, hydrocodone, fentanyl and methadone labels are not part of the morphine label. Only your prescriber should convert you from one opioid to another.

All of these medicines are available as generics, and all of them can vary in cash price from pharmacy to pharmacy. If your prescriber has already chosen the right medicine for you, the useful question is not which opioid is cheapest in general - it is which pharmacy near you has the best price on the exact prescription you were given. Compare the price of your prescription on Rx.com before you fill, and check the price again if your dose or quantity changes.

Morphine sulfate safety, side effects and warnings

All morphine sulfate products carry FDA boxed warnings. The boxed warning on morphine sulfate extended-release tablets (MS Contin) covers six things: addiction, abuse and misuse, which can lead to overdose and death; life-threatening respiratory depression, with the greatest risk when starting the medicine or after a dose increase (older adults and people who are frail, debilitated or have lung disease need especially close monitoring); accidental ingestion, since even one dose, especially by a child, can be fatal; the risks of combining opioids with benzodiazepines or other central nervous system depressants, which can cause profound sedation, respiratory depression, coma and death; neonatal opioid withdrawal syndrome after prolonged use during pregnancy; and the requirements of the Opioid Analgesic REMS program.

Two other extended-release cautions are on the label, but outside the boxed warning. Under Limitations of Use and in the dosing and warnings sections, the label states that extended-release morphine is not indicated as an as-needed (PRN) analgesic, and that crushing, chewing or dissolving the extended-release tablets results in uncontrolled delivery of morphine and can lead to overdose or death. Swallow extended-release tablets and capsules whole.

Other important label warnings include a pharmacokinetic interaction with P-glycoprotein (P-gp) inhibitors such as quinidine: the label states that concomitant use of P-gp inhibitors can increase morphine exposure by about two-fold and can increase the risk of hypotension, respiratory depression, profound sedation, coma and death. The label also warns about adrenal insufficiency, severe low blood pressure, and risks in people with a head injury or increased pressure in the skull. Morphine is contraindicated in known or suspected gastrointestinal obstruction or paralytic ileus, in significant respiratory depression, in acute or severe bronchial asthma in an unmonitored setting, with MAO inhibitors taken within the past 14 days, and in people with a known hypersensitivity to morphine; serotonin syndrome can occur with serotonergic medicines. The most common side effects are constipation (which often persists and usually needs a bowel plan), nausea, vomiting, drowsiness, dizziness, sweating and itching. Keep naloxone on hand if you or someone in your household is at risk of overdose, store morphine locked and away from children, and never stop it abruptly after long-term use - your prescriber should taper you off. This page is educational and is not a substitute for medical advice; talk with your doctor or pharmacist about your own situation.