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Norethindrone-Eth Estradiol Disp Pack — prescription drug image

Norethindrone-Eth Estradiol

Norethindrone-Eth Estradiol 28 Tablets

Women's Health Care
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What is Norethindrone-Eth Estradiol?

Jinteli is used to treat and control the symptoms of menopause. Ethinyl Estradiol-Norethindrone is the generic version of Jinteli. On average, Jinteli is priced at approximately $106 for a supply of 28, 1 mg-5 mcg tablets. You can use our free Singlecare savings card to receive a Jinteli discount of up to 80% at a local pharmacy that participates with Singlecare.

Prescription savings · · · ·

What is Norethindrone-Eth Estradiol ?

Jinteli is used to treat and control the symptoms of menopause. Ethinyl Estradiol-Norethindrone is the generic version of Jinteli. On average, Jinteli is priced at approximately $106 for a supply of 28, 1 mg-5 mcg tablets. You can use our free Singlecare savings card to receive a Jinteli discount of up to 80% at a local pharmacy that participates with Singlecare.
  • Heavy vaginal bleeding
  • Chest pain or tightness, trouble breathing, coughing up blood
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Numbness or weakness in your arm or leg, or on one side of your body
  • Dark urine or pale stools, loss of appetite, yellow skin or eyes
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Breast lumps, pain, swelling, tenderness, or discharge
  • Pain in your lower leg (calf)
  • Fast or pounding heartbeat
  • Sudden or severe headache, problems with vision, speech, or walking
  • Sudden and severe stomach pain, nausea, vomiting, lightheadedness
  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you had a baby within 4 weeks before you start using this medicine. Tell your doctor if you have kidney disease, asthma, cervical cancer, diabetes, epilepsy, gallbladder problems, heart or blood vessel disease, high cholesterol, or a family history of breast cancer or depression. Tell your doctor if you smoke, wear contact lenses, or if you will be having a surgery with a prolonged period of inactivity.
  • This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsPossible risk of cancer (including cancer of the breast, endometrium, ovaries, or cervix)Liver problemsChanges in visionGallbladder diseaseHigh cholesterol in the bloodHigh blood pressure
  • This medicine will not protect you from HIV/AIDS or other sexually transmitted diseases.
  • You might have some light bleeding or spotting when you first start using this medicine. This is usually normal and should not last long. However, if you have heavy bleeding or the bleeding lasts more than seven days in a row, call your doctor€™s office.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is norethindrone and ethinyl estradiol used for?
It is a combined oral contraceptive that is FDA approved to prevent pregnancy. A few norethindrone acetate and ethinyl estradiol products are also approved to treat moderate acne vulgaris in females at least 15 years old who want an oral contraceptive and have not responded to topical acne medicines, and that use applies only to the products whose own labels list it. Separate, differently dosed norethindrone acetate plus ethinyl estradiol products such as Jinteli and Fyavolv are menopause hormone-therapy tablets, approved for moderate-to-severe hot flashes and night sweats of menopause and for preventing osteoporosis after menopause. Clinicians sometimes prescribe combined pills for other menstrual conditions that are not on the FDA label; that is a decision to make with your own provider.
How long does it take for norethindrone-ethinyl estradiol birth control to be effective?
It depends on when in your cycle you start the pack. Depending on the start day, you may need a backup method such as condoms for about the first week. The patient leaflet that comes with your specific product spells out exactly when protection begins and whether backup is needed, and your pharmacist can walk you through it. Once you are established on the pill, taking it at the same time every day is what keeps it working.
What are the most common side effects of norethindrone and ethinyl estradiol?
The side effects people report most often are nausea, breast tenderness, headache, spotting or breakthrough bleeding (especially in the first few months), changes in weight or appetite, and mood changes. Many of these ease as your body adjusts. Tell your provider if side effects are bothersome or do not go away. Seek care right away for warning signs of a serious problem such as chest pain, shortness of breath, severe leg pain or swelling, a sudden severe headache, vision changes, or weakness, numbness, or slurred speech.
What happens if I miss a dose of norethindrone-ethinyl estradiol?
What to do depends on your specific product, how many pills you missed, and where you are in the pack, so check the patient leaflet that came with your pills. As a general rule, a missed pill can reduce protection against pregnancy, and you may need to use a backup method such as condoms for several days. Do not guess. Call your pharmacist or your provider, who can tell you exactly what to do for the pack you are on.
Who should not take norethindrone and ethinyl estradiol?
Do not take it if you smoke and are over 35, because combined oral contraceptives carry a boxed warning about serious cardiovascular events from smoking. It is also contraindicated if you have or have had blood clots or a known clotting disorder, uncontrolled high blood pressure, ischemic heart disease, migraine with aura, liver tumors or active liver disease, undiagnosed abnormal vaginal bleeding, breast cancer or another estrogen-dependent cancer, or if you are pregnant. Labels also contraindicate use with hepatitis C drug combinations containing ombitasvir, paritaprevir, and ritonavir. Tell your provider about every medicine and supplement you take, since drugs like rifampin, some seizure medicines, and St. John's wort can make the pill less effective.
How much does Norethindrone-Eth Estradiol cost without insurance?
The price of Norethindrone-Eth Estradiol without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Norethindrone-Eth Estradiol?
Common side effects of Norethindrone-Eth Estradiol may include: Heavy vaginal bleeding, Chest pain or tightness, trouble breathing, coughing up blood, Rapid weight gain, swelling in your hands, ankles, or feet, Numbness or weakness in your arm or leg, or on one side of your body, Dark urine or pale stools, loss of appetite, yellow skin or eyes. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Norethindrone-Eth Estradiol?
Generic versions may be available for Norethindrone-Eth Estradiol. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Norethindrone-Eth Estradiol on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Norethindrone-Eth Estradiol?
The cheapest pharmacy for Norethindrone-Eth Estradiol depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Norethindrone-Eth Estradiol near you.

Norethindrone-Eth Estradiol Coupons & Prices

Norethindrone-Eth Estradiol 28 Tablets

Women's Health Care
Licensed US providers · Online visit in minutes
Norethindrone-Eth Estradiol Disp Pack — prescription drug image
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Use a free Rx.com norethindrone-eth-estradiol coupon to compare cash prices for this combined birth control pill at more than 60,000 pharmacies before you fill it. Norethindrone (or norethindrone acetate) and ethinyl estradiol is a widely used combined oral contraceptive, and FDA-approved generic versions of several of these products are available. Cash prices are set by each pharmacy, so the price for the exact same pill pack can differ a lot from one store to the next, which is why it pays to check. Enter your ZIP code above to see today's price near you and print, text, or email your coupon.

What norethindrone and ethinyl estradiol is and how it works

Norethindrone (or norethindrone acetate) and ethinyl estradiol is a combined oral contraceptive, often shortened to "COC." It pairs an estrogen (ethinyl estradiol) with a progestin (norethindrone or norethindrone acetate). Taken as directed, it is FDA approved to prevent pregnancy. A few norethindrone acetate and ethinyl estradiol products carry an additional FDA-approved use: treatment of moderate acne vulgaris in females at least 15 years old who also want an oral contraceptive, have started having periods, and have not responded to topical acne medicines. That acne indication belongs only to the specific products whose labels list it, not to every pack in this family.

Separate, differently dosed norethindrone acetate plus ethinyl estradiol products, such as Jinteli and Fyavolv, are menopause hormone-therapy tablets rather than contraceptives. They are approved for moderate-to-severe hot flashes and night sweats of menopause and for preventing osteoporosis after menopause. They carry a lower amount of ethinyl estradiol than birth control packs do, and they are a different medicine with a different label, not an interchangeable version of the birth control pill.

Many contraceptive packs are labeled "Fe," which means the non-hormonal reminder tablets contain ferrous fumarate (iron). The iron does not add contraceptive protection. Doses and pill schedules vary a lot between products, so always follow the patient leaflet that comes with the specific pack your pharmacy dispenses, and ask your pharmacist if the pack looks different from your last fill.

Norethindrone-ethinyl estradiol cost and coupon savings

FDA-approved generics exist for many norethindrone (or norethindrone acetate) and ethinyl estradiol products, and a generic is what most pharmacies dispense. Without insurance, though, there is no single "price" for it. Pharmacies set their own cash prices, and two stores a few miles apart can charge very different amounts for an identical pack. Discount-card pricing also varies by pharmacy contract. That spread is the entire reason comparing is worth 30 seconds of your time.

Rx.com compares cash prices across more than 60,000 U.S. pharmacies, including big chains, grocery stores, and independents. Enter your ZIP above to see today's price near you, then show the coupon at the counter. The coupon is free, is not insurance, and is used instead of insurance rather than with it. If your plan covers contraception with no copay, that may still be your cheapest route, so it is worth checking both.

One product to know about: Lo Loestrin Fe has no FDA-approved generic equivalent. It is available only as the brand, so a pharmacist cannot substitute a generic for it the way they can for many other norethindrone and ethinyl estradiol packs. If you are prescribed Lo Loestrin Fe, compare cash prices for the brand itself, and ask your clinician whether a product that does have a generic is appropriate for you. Any manufacturer savings program is run on the brand's own official website with its own eligibility terms, which change over time and typically exclude government insurance.

Brands and alternatives

Norethindrone and ethinyl estradiol is sold under many brand and generic labels, and the strengths are not all the same. Commonly dispensed U.S. products include Lo Loestrin Fe, Junel and Junel Fe, Microgestin and Microgestin Fe, Blisovi Fe, Larin Fe, Aurovela Fe, Nortrel, and Balziva. Ortho-Novum, the original brand many people remember, is no longer marketed, though equivalent generic formulations still are. Because the estrogen and progestin doses differ between these products, your pharmacist can only substitute one for another when they are approved as equivalent, so never assume two look-alike packs are the same pill.

Other options in the same family include levonorgestrel and ethinyl estradiol and norgestimate and ethinyl estradiol, which use a different progestin. If estrogen is not a good fit for you, for example because you smoke and are over 35, have migraine with aura, or have a history of blood clots, a progestin-only option such as norethindrone may be discussed instead. Which pill is right for you is a decision for you and your clinician, not something to switch on your own. Compare prices for any of these on Rx.com before you fill.

Safety information you should know

Combined oral contraceptives carry a boxed warning: cigarette smoking increases the risk of serious cardiovascular events from combined oral contraceptive use, and that risk rises with age and with the number of cigarettes smoked. These pills should not be used by women over 35 who smoke. Other serious risks include blood clots in the legs or lungs, stroke, heart attack, and high blood pressure. Risk is higher with obesity, an inherited clotting disorder, or migraine with aura.

This medicine is not for everyone. It is contraindicated if you have or have had blood clots or a known clotting disorder, uncontrolled high blood pressure, ischemic heart disease, migraine with aura, liver tumors or active liver disease, undiagnosed abnormal vaginal bleeding, breast cancer or another estrogen-dependent cancer, or if you are pregnant. Current labels also contraindicate use with hepatitis C drug combinations containing ombitasvir, paritaprevir, and ritonavir because of the risk of liver enzyme elevations. Some medicines, including rifampin, certain seizure medicines, and St. John's wort, can make the pill less effective at preventing pregnancy. Get medical help right away for chest pain, shortness of breath, severe leg pain or swelling, a sudden severe headache, vision changes, weakness or numbness, or slurred speech. This pill does not protect against HIV or other sexually transmitted infections. The menopause hormone-therapy versions of this combination carry their own separate estrogen-plus-progestin boxed warnings. This page is information, not medical advice. Talk with your doctor or pharmacist about your own health history before starting or stopping any birth control.

Sources & accuracy

This Norethindrone-Eth Estradiol information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Norethindrone-Eth Estradiol on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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