Rinvoq
Rinvoq 30 Tablets Extended Release 24 Hour
What is Rinvoq?
Rinvoq (upadacitinib) is a prescription medication manufactured by AbbVie Inc. It is a Janus kinase (JAK) inhibitor used for treating moderate to severe rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in adults when one or more treatments have failed to provide sufficient relief. Rinvoq works by inhibiting specific enzymes involved in the inflammatory process, thereby reducing inflammation and other symptoms associated with these conditions.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain that may spread, trouble breathing, coughing up blood, unusual sweating, fainting
- Dark urine or pale stools, nausea, vomiting, loss of appetite, yellow skin or eyes
Warnings
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting this medicine. Use an effective form of birth control during treatment with this medicine and for at least 4 weeks after the last dose.
- Do not breastfeed during treatment with this medicine and for at least 6 days after the last dose.
- Tell your doctor if you have kidney disease, liver disease (including hepatitis B or C), blood problems, cancer or a history of cancer, diabetes, lung disease, HIV, stomach or bowel problem (including diverticulitis), or a history of tuberculosis. Tell your doctor if you have a current infection or an infection that keeps coming back, or if you are a current or past smoker.
- This medicine may cause the following problems:Increased risk of serious infections (bacterial, fungal, viral), including herpes infection or shinglesIncreased risk of cancer (including lymphoma, lung cancer, skin cancer)Increased risk of serious heart or blood vessel disease (including heart attack, stroke)Increased risk of blood clots (including arterial thrombosis, deep vein thrombosis, pulmonary embolism), especially in patients with rheumatoid arthritis who are 50 years of age and older and with a heart or blood vessel diseaseStomach or bowel perforation (tear or hole)High cholesterol in the blood
- You will need to have a skin test for tuberculosis (TB) before you start this medicine. Tell your doctor if you or anyone in your home has ever had a positive TB skin test or been exposed to TB.
Prescription savings · · · ·
What is Rinvoq ?
Rinvoq (upadacitinib) is a prescription medication manufactured by AbbVie Inc. It is a Janus kinase (JAK) inhibitor used for treating moderate to severe rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in adults when one or more treatments have failed to provide sufficient relief. Rinvoq works by inhibiting specific enzymes involved in the inflammatory process, thereby reducing inflammation and other symptoms associated with these conditions.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain that may spread, trouble breathing, coughing up blood, unusual sweating, fainting
- Dark urine or pale stools, nausea, vomiting, loss of appetite, yellow skin or eyes
- Fever, chills, cough, runny or stuffy nose, sore throat, night sweats, body aches
- Numbness or weakness in your arm or leg, or on one side of your body
- Pain, redness, swelling, or tenderness in the arms or legs
- Skin or mole changes, sores that do not heal
- Stomach pain, cramping, bloody stools
- Unusual bleeding, bruising, or weakness
- Sores, reddish patch or irritated area, shiny bump, or pink growth on the skin
- Sudden or severe headache, problems with vision, speech, or walking
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting this medicine. Use an effective form of birth control during treatment with this medicine and for at least 4 weeks after the last dose.
- Do not breastfeed during treatment with this medicine and for at least 6 days after the last dose.
- Tell your doctor if you have kidney disease, liver disease (including hepatitis B or C), blood problems, cancer or a history of cancer, diabetes, lung disease, HIV, stomach or bowel problem (including diverticulitis), or a history of tuberculosis. Tell your doctor if you have a current infection or an infection that keeps coming back, or if you are a current or past smoker.
- This medicine may cause the following problems:Increased risk of serious infections (bacterial, fungal, viral), including herpes infection or shinglesIncreased risk of cancer (including lymphoma, lung cancer, skin cancer)Increased risk of serious heart or blood vessel disease (including heart attack, stroke)Increased risk of blood clots (including arterial thrombosis, deep vein thrombosis, pulmonary embolism), especially in patients with rheumatoid arthritis who are 50 years of age and older and with a heart or blood vessel diseaseStomach or bowel perforation (tear or hole)High cholesterol in the blood
- You will need to have a skin test for tuberculosis (TB) before you start this medicine. Tell your doctor if you or anyone in your home has ever had a positive TB skin test or been exposed to TB.
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Rinvoq Coupons & Prices
Rinvoq 30 Tablets Extended Release 24 Hour
4 ED medications in one dose
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Rinvoq (upadacitinib) is a brand-name Janus kinase (JAK) inhibitor prescribed for several inflammatory and autoimmune conditions, and because no generic version is available, the brand-name price applies no matter where you fill it. If you're searching for a Rinvoq coupon, the free Rx.com cash-price coupon can be used at your local pharmacy alongside — or instead of — AbbVie's manufacturer savings program, and it works even if you're uninsured, on Medicare, or your savings card is declined. Enter your ZIP code above to see today's Rinvoq price near you.
What Is Rinvoq (Upadacitinib) and How Does It Work?
Rinvoq is an oral Janus kinase (JAK) inhibitor that works by blocking enzymes involved in the body's inflammatory signaling. It's available as Rinvoq extended-release tablets and Rinvoq LQ oral solution, and there is currently no generic version of upadacitinib.
- Moderately to severely active rheumatoid arthritis in adults who haven't responded well to, or can't tolerate, one or more TNF blocker medications
- Active psoriatic arthritis (age 2 and older)
- Active ankylosing spondylitis and active non-radiographic axial spondyloarthritis
- Refractory moderate-to-severe atopic dermatitis in adults and children 12+ whose disease isn't adequately controlled by other systemic treatments, including biologics
- Moderately to severely active ulcerative colitis and Crohn's disease in adults
- Active polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis (age 2+)
- Giant cell arteritis in adults
For several of these conditions, FDA labeling requires that patients try other therapies, such as TNF blockers, first — Rinvoq isn't typically a first-line option.
Rinvoq Coupon: Manufacturer Savings Card vs. Rx.com Cash Price
AbbVie, the manufacturer of Rinvoq, offers its own Rinvoq Complete savings program through the official Rinvoq website. Like most manufacturer copay cards, it's generally limited to patients with commercial (private) insurance, and the exact terms and eligibility rules can change, so check the manufacturer's site directly for current details.
If you don't have commercial insurance — for example, you're uninsured, covered by Medicare or Medicaid, or your manufacturer card is declined at the pharmacy counter — the Rx.com cash-price coupon is a free alternative that works at participating pharmacies regardless of insurance status. Because Rinvoq has no generic equivalent, it's worth comparing your cash coupon price against your insurance copay, if you have one, before every fill. Enter your ZIP code above to see today's price at pharmacies near you.
How Rinvoq Compares to Other Options
Rinvoq belongs to a class of oral JAK inhibitors used for similar inflammatory conditions, including Xeljanz (tofacitinib) and Olumiant (baricitinib) for rheumatoid arthritis, and Cibinqo (abrocitinib) for atopic dermatitis. Depending on the condition being treated, your doctor may also consider biologic injectables such as Humira (adalimumab) or Skyrizi (risankizumab), or other oral options like Otezla (apremilast) for psoriatic arthritis.
Which option makes sense depends on your specific diagnosis, prior treatments, and insurance coverage — this is a decision to make with your prescriber, not a straight price comparison, since these medications aren't interchangeable.
Rinvoq Safety Information and Boxed Warning
Rinvoq carries a boxed warning — shared across JAK inhibitor medications — for serious infections (including bacterial, fungal, viral, and opportunistic infections such as tuberculosis), increased risk of death, cancer (including lymphoma), major adverse cardiovascular events, and blood clots (including DVT, pulmonary embolism, and arterial thrombosis), some of which have been fatal. Doctors typically test for tuberculosis before and during treatment, and Rinvoq shouldn't be started in patients with an active infection. Extra caution applies to patients age 65 and older, current or former smokers, and those with existing heart or clotting risk factors.
The most common side effects reported include upper respiratory infections, nausea, elevated liver enzymes, elevated cholesterol/lipid levels, acne, and headache. This is general information, not medical advice — talk to your doctor or pharmacist about whether Rinvoq is right for you and what to watch for.
This Rinvoq information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Rinvoq on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.