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Timolol Maleate

Timolol Maleate 5ML of 0.5%

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What is Timolol Maleate?

Timoptic is used to treat glaucoma and high pressure in the eyes. Timolol ophthalmic is the generic version of Timoptic. The average Timoptic cost is expensive, at about $509 for a supply of 60, 0.5% ophthalmic solution. However, you can significantly reduce the Timoptic price by using our free Singlecare coupon card at participating local pharmacies.

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What is Timolol Maleate ?

Timoptic is used to treat glaucoma and high pressure in the eyes. Timolol ophthalmic is the generic version of Timoptic. The average Timoptic cost is expensive, at about $509 for a supply of 60, 0.5% ophthalmic solution. However, you can significantly reduce the Timoptic price by using our free Singlecare coupon card at participating local pharmacies.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, trouble breathing
  • Severe eye irritation or inflammation
  • Slow or uneven heartbeat
  • Swelling in your hands, ankles, or feet
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, asthma, severe COPD, diabetes, heart disease, heart failure, slow heartbeat, stroke, myasthenia gravis, thyroid problems, or a history of asthma.
  • Ophthalmic routeIf you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is timolol maleate used for?
Timolol maleate eye drops are used to lower elevated pressure inside the eye (intraocular pressure) in people with ocular hypertension or open-angle glaucoma. An oral form is also used for high blood pressure, prevention of a repeat heart attack, and migraine prevention; the original brand (Blocadren) has been discontinued, but generic oral tablets remain available in the US.
Is timolol maleate a beta blocker?
Yes. Timolol maleate is a nonselective beta-adrenergic receptor blocking agent, commonly called a beta-blocker. In eye drop form it lowers eye pressure by reducing how much fluid the eye produces.
What are the side effects of timolol maleate eye drops?
Because the drops are absorbed into the bloodstream, timolol can cause beta-blocker effects such as a slow or irregular heartbeat, low blood pressure, dizziness, and breathing problems like bronchospasm, especially in people with asthma or COPD. It can also mask the warning signs of low blood sugar in people with diabetes. Report chest pain, trouble breathing, a slow or irregular heartbeat, severe dizziness, or fainting to your provider.
Can timolol eye drops affect your heart rate or blood pressure?
Yes. Even though they are placed in the eye, timolol drops are absorbed systemically and can slow the heart rate, cause heart block, and lower blood pressure. Timolol is contraindicated in people with certain heart rhythm problems or heart failure. Tell your doctor about any heart or blood pressure conditions before starting it.
How long does timolol maleate take to lower eye pressure?
Timolol eye drops begin lowering intraocular pressure within a short time of dosing, and your eye doctor will recheck your pressure at follow-up visits to confirm it is working. Use the drops exactly as prescribed and do not stop without talking to your provider. Ask your eye doctor what to expect for your specific situation.
How much does Timolol Maleate cost without insurance?
The price of Timolol Maleate without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 37% off retail prices with a free Rx.com coupon.
What are the common side effects of Timolol Maleate?
Common side effects of Timolol Maleate may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Chest pain, trouble breathing, Severe eye irritation or inflammation, Slow or uneven heartbeat, Swelling in your hands, ankles, or feet. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Timolol Maleate?
Generic versions may be available for Timolol Maleate. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Timolol Maleate on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Timolol Maleate?
The cheapest pharmacy for Timolol Maleate depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Timolol Maleate near you.

Timolol Maleate Coupons & Prices

Timolol Maleate 5ML of 0.5%

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Timolol Maleate Bottle — prescription drug image
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Timolol Maleate 5ml of 0.5% (1)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a timolol maleate coupon? Timolol maleate is a widely used, low-cost generic beta-blocker, most often prescribed as eye drops to lower elevated pressure inside the eye in ocular hypertension and open-angle glaucoma. Because it is generic, cash prices are already modest, but what you pay can vary a lot from one pharmacy to the next. Rx.com compares live discount prices at more than 60,000 pharmacies so you can find the lowest price near you. Enter your ZIP above to see today's price and print or text yourself a free coupon.

What is timolol maleate and how does it work?

Timolol maleate is a nonselective beta-adrenergic receptor blocking agent (a beta-blocker). In its most common form, the ophthalmic (eye drop or gel) solution, it lowers elevated intraocular pressure (IOP) by reducing the amount of fluid the eye produces. It is FDA-approved to treat ocular hypertension and open-angle glaucoma, and it is sold under brand names such as Timoptic, Timoptic-XE, and Istalol. (Betimol is a related eye drop, but its active ingredient is timolol hemihydrate, a different salt form, so it is not the same product as timolol maleate.) Timolol is also a component of combination eye drops like Cosopt (dorzolamide/timolol) and Combigan (brimonidine/timolol).

An oral form was once widely used for high blood pressure, prevention of a second heart attack after a myocardial infarction, and migraine prevention. The original brand, Blocadren, has been discontinued, but generic timolol maleate oral tablets (5 mg, 10 mg, and 20 mg) remain FDA-approved and available in the United States. This page focuses on the ophthalmic form most people mean when they search for "timolol maleate."

How much does generic timolol maleate cost, and can a coupon help?

Timolol maleate is available as a generic (generic_available: yes), so it is already one of the more affordable glaucoma medications. Even so, the cash price without insurance can differ widely between pharmacies in the same town, which is exactly why comparing matters. A pharmacy that looks convenient is not always the cheapest, and a free discount coupon can bring the price down further at many locations.

Rx.com does not set the price; the live price is shown on this page. Enter your ZIP above to see today's price at pharmacies near you and to grab a free coupon you can use at the counter. There is no manufacturer savings card for generic timolol maleate, so a pharmacy discount coupon is usually the most reliable way to save on the cash price.

Timolol maleate vs. other glaucoma medications

Timolol is often one of the first medications tried for elevated eye pressure, but it is not the only option, and some people use it alongside another drug. Related medications your eye doctor may consider include:

  • Latanoprost — a prostaglandin analog eye drop, often used once daily.
  • Dorzolamide — a carbonic anhydrase inhibitor eye drop.
  • Brimonidine tartrate — an alpha agonist eye drop.
  • Dorzolamide/timolol and brimonidine/timolol — combination drops that pair timolol with a second medicine in one bottle.

Which medication is right for you depends on your eye pressure, other health conditions, and how well you tolerate each drop. Compare prices for any of these on Rx.com by entering your ZIP.

Important safety information

Timolol maleate has no FDA boxed warning, but it is not harmless. Even as eye drops, the medicine is absorbed into the bloodstream and can cause the same serious heart and lung effects as an oral beta-blocker, including slowed heart rate (bradycardia), heart block, worsening heart failure, low blood pressure, and narrowing of the airways (bronchospasm). Because of this, it is contraindicated in people with asthma or severe COPD, certain slow or abnormal heart rhythms (such as sinus bradycardia or second- or third-degree AV block), and overt heart failure or cardiogenic shock. It can also mask the warning signs of low blood sugar in people with diabetes and mask symptoms of an overactive thyroid.

Do not stop a systemic (oral) beta-blocker suddenly, and use timolol alone only when directed for open-angle glaucoma, not angle-closure glaucoma. Tell your provider about all your health conditions and medicines, and seek care right away for chest pain, trouble breathing, a slow or irregular heartbeat, severe dizziness, or fainting. This information is educational and is not medical advice; talk with your doctor or pharmacist about whether timolol maleate is right for you.

Sources & accuracy

This Timolol Maleate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Timolol Maleate on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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