Nabumetone
Nabumetone 500MG
What is Nabumetone?
Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) used primarily to treat inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. It functions by inhibiting enzymes that cause inflammation and pain in the body, providing symptomatic relief. Nabumetone is typically administered orally and is designed for long-term management of arthritic symptoms.Side Effects
- Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
- Rapid weight gain.
- Skin rash or blisters with fever.
Warnings
- Tell your doctor if you are pregnant. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, heart disease, anemia, asthma, high blood pressure, or a history of stomach or bowel problems (including bleeding, ulcers).
- Yellowing of your skin or the whites of your eyes.
- Unusual bleeding, bruising, or weakness.
- Vomiting blood or something that looks like coffee grounds.
Prescription savings · · · ·
What is Nabumetone ?
Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) used primarily to treat inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. It functions by inhibiting enzymes that cause inflammation and pain in the body, providing symptomatic relief. Nabumetone is typically administered orally and is designed for long-term management of arthritic symptoms.- Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
- Rapid weight gain.
- Skin rash or blisters with fever.
- Chest pain that may spread, trouble breathing, coughing up blood, unusual sweating, fainting
- Change in how much or how often you urinate, painful or difficult urination
- Bloody or black, tarry stools, vomiting blood or material that looks like coffee grounds
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Unusual bleeding, bruising, or weakness
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Unusual bleeding, bruising, or weakness.
- Shortness of breath, cold sweat, and bluish-colored skin.
- Swelling in your hands, ankles, or feet.
- Yellowing of your skin or the whites of your eyes.
- Severe stomach pain.
- Sudden or severe headache.
- Rapid weight gain, swelling in your hands, ankles, or feet
- Vomiting blood or something that looks like coffee grounds.
- Tell your doctor if you are pregnant. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, heart disease, anemia, asthma, high blood pressure, or a history of stomach or bowel problems (including bleeding, ulcers).
- Yellowing of your skin or the whites of your eyes.
- Unusual bleeding, bruising, or weakness.
- Vomiting blood or something that looks like coffee grounds.
- Swelling in your hands, ankles, or feet.
- Skin rash or blisters with fever.
- Sudden or severe headache.
- Shortness of breath, cold sweat, and bluish-colored skin.
- Severe stomach pain.
- Rapid weight gain.
- Problems with vision, speech, or walking.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Pain in your lower leg (calf).
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- This medicine may cause the following problems:Increased risk of blood clots, heart attack, stroke, or heart failureStomach or bowel problems (including bleeding, ulcers, or perforation)Liver problemsHigh blood pressureKidney problemsSerious skin reactions, including exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS)
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
Nabumetone Coupons & Prices
Nabumetone 500MG
Nabumetone prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 500mg · Tablet | 60 | $71.99 | $19.10 |
| 750mg · Tablet | 60 | $85.59 | $21.45 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Nabumetone is a prescription nonsteroidal anti-inflammatory drug (NSAID) used to relieve the pain, swelling, and stiffness of osteoarthritis and rheumatoid arthritis. It's only sold as a generic today, and cash prices for it can vary widely from one pharmacy to another, so it pays to compare — enter your ZIP above and Rx.com will check prices at 60,000+ pharmacies for a nabumetone coupon near you.
What Is Nabumetone and How Does It Work?
Nabumetone is an NSAID that reduces the body's production of prostaglandins, chemicals involved in inflammation and pain. It's prescribed as oral tablets to relieve pain, tenderness, swelling, and stiffness from osteoarthritis and rheumatoid arthritis. Nabumetone was originally sold under the brand name Relafen, but Relafen has since been discontinued in the US — today nabumetone is available only as a generic tablet.
Comparing Nabumetone Prices
Because nabumetone is a generic drug, the same medication can be priced very differently depending on which pharmacy fills it. Cash prices, insurance copays, and coupon prices can all differ by pharmacy, so comparing before you fill is worthwhile. Enter your ZIP code above and Rx.com will compare nabumetone prices across pharmacies near you.
Nabumetone vs. Other NSAIDs
Nabumetone is one of several prescription and over-the-counter NSAIDs used for arthritis pain, alongside options like ibuprofen, naproxen, meloxicam, and diclofenac. These drugs work similarly but differ in dosing frequency, how long they take to work, and individual tolerability. Your doctor can help decide which NSAID, and what dose, fits your situation and other health conditions.
- Naproxen — another NSAID often dosed twice daily
- Meloxicam — an NSAID typically taken once daily
- Ibuprofen — a shorter-acting NSAID also available over the counter
Safety Information
Like other NSAIDs, nabumetone carries a boxed warning for an increased risk of serious cardiovascular thrombotic events, including heart attack and stroke, which can occur without warning and can be fatal; it should not be used right before or after heart bypass (CABG) surgery. NSAIDs including nabumetone also carry a boxed warning for the risk of serious gastrointestinal events such as bleeding, ulceration, and perforation of the stomach or intestines, which can happen at any time and without warning symptoms. Don't take nabumetone if you've had an asthma attack or severe allergic reaction after taking aspirin or another NSAID. This is general information, not medical advice — talk with your doctor or pharmacist about whether nabumetone is right for you.
This Nabumetone information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Nabumetone on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.