Indocin
Indocin 237ML of 25MG/5ML
What is Indocin?
Indocin (indomethacin) is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to reduce inflammation, pain, and fever associated with various inflammatory conditions such as arthritis, gout, and bursitis. It works by inhibiting the production of certain chemicals in the body that are involved in inflammation. Indocin is available by prescription and should be used under medical supervision due to potential side effects such as gastrointestinal issues and increased risk of cardiovascular events.Side Effects
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Change in how much or how often you urinate
- Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
Warnings
- Tell your doctor if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
- Tell your doctor if you have kidney disease, liver disease, asthma, bleeding problems, heart disease, high blood pressure, heart failure, or a history of stomach or bowel problems (including bleeding or ulcers), depression, mental illness, epilepsy, or Parkinson disease. Tell your doctor if you smoke or drink alcohol.
- This medicine may cause the following problems:Higher risk of blood clots, heart attack, stroke, or heart failureBleeding and ulcers in your stomach or intestinesLiver damageKidney damageSerious skin reactionsChanges in vision
- Ovulation may be delayed in some women while this medicine is being used. Talk to your doctor if you have concerns about this.
- This medicine may make you drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Prescription savings · · · ·
What is Indocin ?
Indocin (indomethacin) is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to reduce inflammation, pain, and fever associated with various inflammatory conditions such as arthritis, gout, and bursitis. It works by inhibiting the production of certain chemicals in the body that are involved in inflammation. Indocin is available by prescription and should be used under medical supervision due to potential side effects such as gastrointestinal issues and increased risk of cardiovascular events.- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Change in how much or how often you urinate
- Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
- Unusual bleeding, bruising, or weakness
- Chest pain that may spread, trouble breathing, unusual sweating, fainting
- Rapid weight gain, swelling in your hands, ankles, or feet
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Bloody or black, tarry stools, severe stomach pain, vomiting blood or something that looks like coffee grounds
- Tell your doctor if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
- Tell your doctor if you have kidney disease, liver disease, asthma, bleeding problems, heart disease, high blood pressure, heart failure, or a history of stomach or bowel problems (including bleeding or ulcers), depression, mental illness, epilepsy, or Parkinson disease. Tell your doctor if you smoke or drink alcohol.
- This medicine may cause the following problems:Higher risk of blood clots, heart attack, stroke, or heart failureBleeding and ulcers in your stomach or intestinesLiver damageKidney damageSerious skin reactionsChanges in vision
- Ovulation may be delayed in some women while this medicine is being used. Talk to your doctor if you have concerns about this.
- This medicine may make you drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Unusual bleeding, bruising, or weakness
Indocin Coupons & Prices
Indocin 237ML of 25MG/5ML
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
If you're searching for an Indocin coupon, the good news is that indomethacin — the active ingredient in Indocin — has been available as a generic for years, and pharmacy cash prices for it vary widely from one store to the next. Rx.com compares prices for indomethacin across more than 60,000 U.S. pharmacies so you can see which one is charging the least in your area; enter your ZIP above to see today's price before you fill your prescription.
What Is Indocin (Indomethacin) and How Does It Work?
Indocin is a brand name for indomethacin, a nonsteroidal anti-inflammatory drug (NSAID) that works by non-selectively blocking both COX-1 and COX-2 enzymes to reduce the inflammation, pain, and swelling that drive many joint and soft-tissue conditions. Oral indomethacin capsules are FDA-approved to treat moderate-to-severe pain, swelling, and stiffness from osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, as well as acute painful shoulder (bursitis and tendinitis) and flares of acute gouty arthritis. The extended-release capsules (Indocin SR) are approved for those same uses except acute gouty arthritis — the FDA label for the extended-release form specifically states it is not recommended for treating gout flares, so the immediate-release capsules are used for that indication.
A separate injectable product, Indocin I.V., is approved for an unrelated use: closing a patent ductus arteriosus in certain premature infants. That use applies only to the IV form given in a hospital setting and is not something the oral capsules or tablets filled at a retail pharmacy are used for.
Indocin Coupon: Why Comparing Pharmacy Prices Matters
Indomethacin, the active ingredient in Indocin, is available as a generic, and generic drug prices are notorious for swinging widely from one pharmacy to the next even within the same city — a store's cash price depends on which wholesaler it buys from and what it chooses to mark up. That's why searching for an "Indocin coupon" is really a search for the pharmacy charging the least that week, not a fixed number. Rx.com compares prices for indomethacin across more than 60,000 U.S. pharmacies, including major chains and independent stores, so you can see which one is cheapest near you.
Enter your ZIP above to see today's price at pharmacies in your area before you fill an Indocin or generic indomethacin prescription.
Indocin Alternatives: Other NSAIDs and Gout Options
Indomethacin is one of several NSAIDs your provider may consider, and it isn't automatically the right or the only choice. Other commonly prescribed NSAIDs include naproxen, diclofenac, meloxicam, celecoxib (Celebrex), and over-the-counter ibuprofen — all work on the same COX pathway but differ in dosing, potency, and side-effect profile, so switching between them isn't a simple swap without your provider's input.
For gout specifically, colchicine is another option your provider may use, either instead of or alongside an NSAID, particularly for gout flare prevention (a use that is off-label for indomethacin itself). If you're comparing generic indomethacin pricing directly, you can also check the generic indomethacin page.
Indocin Safety Information
Indocin and generic indomethacin carry the boxed warnings required of all prescription NSAIDs: an increased risk of serious cardiovascular events such as heart attack and stroke, which can occur early in treatment and rises with dose and duration (indomethacin should not be used right before or after coronary artery bypass graft surgery), and an increased risk of serious gastrointestinal bleeding, ulcers, and perforation, which can happen without warning and can be fatal. Anyone with a history of NSAID or aspirin hypersensitivity, including aspirin-sensitive asthma, should not take it.
- Should not be used after 20 weeks of pregnancy due to risk to fetal kidney and heart function.
- Can cause drowsiness or dizziness.
- Can interact with blood thinners, aspirin, other NSAIDs, oral corticosteroids, SSRI/SNRI antidepressants (bleeding risk), and lithium.
This is general information, not medical advice — talk with your doctor or pharmacist about whether Indocin is appropriate for you and about any medications or conditions that could interact with it.
This Indocin information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Indocin on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Browse more medications: starting with I · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.