Naproxen Sodium
Naproxen Sodium 550MG
What is Naproxen Sodium?
Naproxen Sodium is a medication used to relieve pain and tenderness. It is often prescribed for conditions like arthritis, muscle aches, and menstrual pain.Side Effects
- Blistering, peeling, red skin rash
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
Warnings
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- This medicine may cause a delay in ovulation for women and may affect their ability to have children. If you plan to have children, talk with your doctor before using this medicine.
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Prescription savings · · · ·
What is Naproxen Sodium ?
Naproxen Sodium is a medication used to relieve pain and tenderness. It is often prescribed for conditions like arthritis, muscle aches, and menstrual pain.- Blistering, peeling, red skin rash
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
- Chest pain that may spread, trouble breathing, unusual sweating, fainting
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Bloody or black, tarry stools, severe stomach pain, vomiting blood or something that looks like coffee grounds
- Rapid weight gain, swelling in your hands, ankles, or feet
- Change in how much or how often you urinate, painful or difficult urination
- Unusual bleeding, bruising, or weakness
- Fever, chills, cough, sore throat, body aches
- Vision changes
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- This medicine may cause a delay in ovulation for women and may affect their ability to have children. If you plan to have children, talk with your doctor before using this medicine.
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Tell any doctor or dentist who treats that you are using this medicine, especially if you have surgery or a procedure.
- Call your doctor if symptoms get worse, pain lasts more than 10 days, or fever lasts more than 3 days.
- This medicine may cause the following problems:Increased risk of blood clots, heart attack, stroke, or heart failureStomach or bowel problems (including bleeding, ulcers, or perforation)Liver problemsKidney problemsHigh blood pressureSerious skin reactions, including exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS)
- Tell your doctor if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
- Tell your doctor if you have kidney disease, liver disease, anemia, asthma, bleeding problems, high blood pressure, heart failure, a recent heart attack, or a history of stomach or bowel problems (including ulcers or bleeding). Tell your doctor if you smoke or drink alcohol.
Naproxen Sodium Coupons & Prices
Naproxen Sodium 550MG
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Looking for a naproxen sodium coupon? Naproxen sodium is a widely used, low-cost generic nonsteroidal anti-inflammatory drug (NSAID) that comes both over the counter (as Aleve) and in higher prescription strengths. Because it is generic, it is already inexpensive at most pharmacies, but the cash price can still vary a lot from one pharmacy to the next, which is exactly why comparing pays off. Enter your ZIP above to see today's price and pull up a free Rx.com discount coupon accepted at more than 60,000 U.S. pharmacies.
What is naproxen sodium and how does it work?
Naproxen sodium is the sodium salt of naproxen, a propionic acid NSAID. It works by lowering the body's production of prostaglandins, the chemical messengers that drive pain, swelling, and fever. The sodium salt dissolves and is absorbed more quickly than plain naproxen, so it may start working a bit faster, though both deliver the same active medicine once in the body.
Prescription naproxen sodium is FDA-approved to relieve the signs and symptoms of osteoarthritis, rheumatoid arthritis, juvenile idiopathic arthritis, and ankylosing spondylitis, and to treat tendinitis, bursitis, acute gout, and pain including primary dysmenorrhea (menstrual cramps). The over-the-counter form (Aleve) is used for the temporary relief of minor aches and pains and to reduce fever. Prescription brand names include Anaprox DS and the extended-release Naprelan.
How much does naproxen sodium cost without insurance?
As a generic, naproxen sodium is one of the more affordable NSAIDs, and the over-the-counter version is sold on store shelves without a prescription. Even so, the cash price for prescription strengths can differ widely between pharmacies in the same town, so it is worth checking before you fill. There is no manufacturer copay savings card for generic naproxen sodium, but you do not need one to save.
Rx.com compares cash prices across more than 60,000 pharmacies and gives you a free discount coupon you can use whether or not you have insurance. Enter your ZIP above to see today's price near you and print, text, or show the coupon at the pharmacy counter.
Naproxen sodium vs. other NSAIDs and pain relievers
Naproxen sodium is closely related to plain naproxen and to the over-the-counter brand Aleve; the main differences are the salt form and how the product is sold. If naproxen is not the right fit, your provider may consider other NSAIDs, each with its own dosing schedule and risk profile:
- Ibuprofen — a shorter-acting NSAID taken more often through the day.
- Meloxicam — a once-daily prescription NSAID often used for arthritis.
- Diclofenac — available as tablets and topical gels for joint pain.
- Celecoxib — a COX-2 selective NSAID that may be gentler on the stomach for some people.
Which option is best depends on your health history, other medicines, and how long you need treatment. This is a comparison of options, not medical advice; talk with your provider or pharmacist about the right choice for you.
Safety and important warnings
Like all NSAIDs, naproxen sodium carries an FDA boxed warning. First, NSAIDs can raise the risk of serious and potentially fatal heart attack and stroke, a risk that can appear early in treatment and grow with longer use; naproxen sodium should not be used for pain right before or after coronary artery bypass graft (CABG) surgery. Second, NSAIDs can cause serious gastrointestinal bleeding, ulcers, and tears in the stomach or intestines, which can happen without warning and are more common in older adults.
Other cautions include high blood pressure, fluid retention and heart failure, kidney or liver injury, serious skin reactions, and allergic reactions. It should generally be avoided in pregnancy from about 20 weeks on (and especially at 30 weeks and later). Use the lowest effective dose for the shortest time needed. This is a summary, not a complete list, and not medical advice; read the label and check with your provider or pharmacist before starting naproxen sodium.
This Naproxen Sodium information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Naproxen Sodium on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.